Gene description for Ugdh
Gene name UDP-glucose 6-dehydrogenase
Gene symbol Ugdh
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Ugdh
ExoCarta ExoCarta_83472
Vesiclepedia VP_83472
Entrez Gene 83472
UniProt O70199  
 Ugdh identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Ugdh
Molecular Function
    UDP-glucose 6-dehydrogenase activity GO:0003979 IDA
    UDP-glucose 6-dehydrogenase activity GO:0003979 IEA
    UDP-glucose 6-dehydrogenase activity GO:0003979 ISO
    identical protein binding GO:0042802 ISO
    NAD binding GO:0051287 IEA
Biological Process
    gastrulation with mouth forming second GO:0001702 IEA
    gastrulation with mouth forming second GO:0001702 ISO
    gastrulation with mouth forming second GO:0001702 ISO
    gastrulation with mouth forming second GO:0001702 ISS
    glycosaminoglycan biosynthetic process GO:0006024 IBA
    UDP-glucuronate biosynthetic process GO:0006065 IEA
    UDP-glucuronate biosynthetic process GO:0006065 ISO
    UDP-glucuronate biosynthetic process GO:0006065 ISS
    heparan sulfate proteoglycan biosynthetic process GO:0015012 IEA
    heparan sulfate proteoglycan biosynthetic process GO:0015012 ISO
    heparan sulfate proteoglycan biosynthetic process GO:0015012 ISS
    chondroitin sulfate biosynthetic process GO:0030206 IEA
    chondroitin sulfate biosynthetic process GO:0030206 ISO
    chondroitin sulfate biosynthetic process GO:0030206 ISS
    protein hexamerization GO:0034214 ISO
    protein hexamerization GO:0034214 ISS
    neuron development GO:0048666 ISO
    neuron development GO:0048666 ISS
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Ugdh in sEVs
1
Experiment ID 35
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|CD81|CD63
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Ugdh
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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