Gene description for Ceacam1
Gene name	carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein)
Gene symbol	Ceacam1
Other names/aliases	BGPR Bgp CD66a Ccam1
Species	Rattus norvegicus
Database cross references - Ceacam1
ExoCarta	ExoCarta_81613
Vesiclepedia	VP_81613
Entrez Gene	81613
UniProt	P16573
Ceacam1 identified in sEVs derived from the following tissue/cell type
Hepatocytes	19367702

Gene ontology annotations for Ceacam1

Molecular Function     actin binding GO:0003779 ISO     granulocyte colony-stimulating factor receptor binding GO:0005130 ISO     protein binding GO:0005515 IPI     calmodulin binding GO:0005516 IDA     bile acid transmembrane transporter activity GO:0015125 IDA     kinase binding GO:0019900 ISO     protein kinase binding GO:0019901 IPI     protein phosphatase binding GO:0019903 ISO     filamin binding GO:0031005 ISO     Toll-like receptor binding GO:0035325 ISO     identical protein binding GO:0042802 IMP     identical protein binding GO:0042802 ISO     protein homodimerization activity GO:0042803 IDA     protein dimerization activity GO:0046983 IDA     protein tyrosine kinase binding GO:1990782 IBA     protein tyrosine kinase binding GO:1990782 ISO Biological Process     regulation of cell growth GO:0001558 IDA     blood vessel development GO:0001568 ISO     blood vessel development GO:0001568 ISS     negative regulation of cytokine production GO:0001818 ISO     negative regulation of T cell mediated cytotoxicity GO:0001915 ISO     negative regulation of T cell mediated cytotoxicity GO:0001915 ISS     regulation of immune system process GO:0002682 IBA     negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 ISO     negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target GO:0002859 ISS     negative regulation of protein kinase activity GO:0006469 ISO     negative regulation of protein kinase activity GO:0006469 ISS     cell adhesion GO:0007155 IDA     cell adhesion GO:0007155 IDA     homophilic cell adhesion via plasma membrane adhesion molecules GO:0007156 IDA     signal transduction GO:0007165 IBA     regulation of endothelial cell migration GO:0010594 ISO     regulation of endothelial cell migration GO:0010594 ISS     bile acid and bile salt transport GO:0015721 IDA     regulation of cell migration GO:0030334 ISO     regulation of cell migration GO:0030334 ISS     negative regulation of granulocyte differentiation GO:0030853 ISO     negative regulation of granulocyte differentiation GO:0030853 ISS     negative regulation of interleukin-1 production GO:0032692 ISO     negative regulation of interleukin-1 production GO:0032692 ISS     cellular response to insulin stimulus GO:0032869 IDA     common myeloid progenitor cell proliferation GO:0035726 ISO     common myeloid progenitor cell proliferation GO:0035726 ISS     insulin receptor internalization GO:0038016 IDA     granulocyte colony-stimulating factor signaling pathway GO:0038158 ISO     granulocyte colony-stimulating factor signaling pathway GO:0038158 ISS     regulation of epidermal growth factor receptor signaling pathway GO:0042058 IMP     regulation of epidermal growth factor receptor signaling pathway GO:0042058 ISO     regulation of epidermal growth factor receptor signaling pathway GO:0042058 ISS     negative regulation of T cell proliferation GO:0042130 ISO     negative regulation of vascular permeability GO:0043116 ISO     negative regulation of vascular permeability GO:0043116 ISS     negative regulation of cytotoxic T cell degranulation GO:0043318 ISO     negative regulation of cytotoxic T cell degranulation GO:0043318 ISS     positive regulation of MAP kinase activity GO:0043406 IDA     wound healing, spreading of cells GO:0044319 ISO     wound healing, spreading of cells GO:0044319 ISS     cell-cell junction organization GO:0045216 ISO     regulation of endothelial cell differentiation GO:0045601 ISO     regulation of endothelial cell differentiation GO:0045601 ISS     negative regulation of osteoclast differentiation GO:0045671 ISO     negative regulation of fatty acid biosynthetic process GO:0045717 IMP     negative regulation of bone resorption GO:0045779 ISO     negative regulation of T cell receptor signaling pathway GO:0050860 ISO     negative regulation of T cell receptor signaling pathway GO:0050860 ISS     negative regulation of lipid biosynthetic process GO:0051055 ISO     negative regulation of lipid biosynthetic process GO:0051055 ISS     regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051896 IDA     regulation of blood vessel remodeling GO:0060312 ISO     regulation of blood vessel remodeling GO:0060312 ISS     regulation of ERK1 and ERK2 cascade GO:0070372 IDA     negative regulation of platelet aggregation GO:0090331 ISO     negative regulation of platelet aggregation GO:0090331 ISS     cell-cell adhesion via plasma-membrane adhesion molecules GO:0098742 IDA     insulin catabolic process GO:1901143 IMP     insulin catabolic process GO:1901143 ISO     insulin catabolic process GO:1901143 ISS     regulation of homophilic cell adhesion GO:1903385 IDA     positive regulation of homophilic cell adhesion GO:1903387 IDA     regulation of sprouting angiogenesis GO:1903670 ISO     regulation of sprouting angiogenesis GO:1903670 ISS     negative regulation of hepatocyte proliferation GO:2000346 IMP     negative regulation of hepatocyte proliferation GO:2000346 ISO     negative regulation of hepatocyte proliferation GO:2000346 ISS     positive regulation of vasculogenesis GO:2001214 ISO     positive regulation of vasculogenesis GO:2001214 ISS Subcellular Localization     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     cell-cell junction GO:0005911 IDA     cell-cell junction GO:0005911 ISO     cell-cell junction GO:0005911 ISS     adherens junction GO:0005912 IDA     external side of plasma membrane GO:0009897 ISO     basal plasma membrane GO:0009925 IDA     basal plasma membrane GO:0009925 IEA     cell surface GO:0009986 IBA     cell surface GO:0009986 ISO     cell surface GO:0009986 ISS     membrane GO:0016020 IEA     membrane GO:0016020 ISO     apical plasma membrane GO:0016324 IDA     apical plasma membrane GO:0016324 ISO     lateral plasma membrane GO:0016328 IDA     lateral plasma membrane GO:0016328 IEA     cell junction GO:0030054 IDA     cell junction GO:0030054 ISO     transport vesicle GO:0030133 IEA     microvillus membrane GO:0031528 IEA     T cell receptor complex GO:0042101 ISO     T cell receptor complex GO:0042101 ISS     ciliary membrane GO:0060170 ISO