Gene description for LAP3
Gene name leucine aminopeptidase 3
Gene symbol LAP3
Other names/aliases LAP-3
PEPS
Species Bos taurus
 Database cross references - LAP3
ExoCarta ExoCarta_781648
Entrez Gene 781648
UniProt P00727  
 LAP3 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for LAP3
Molecular Function
    metalloexopeptidase activity GO:0008235 IEA
    peptidase activity GO:0008233 ISS
    manganese ion binding GO:0030145 IEA
    aminopeptidase activity GO:0004177 IEA
Biological Process
    proteolysis GO:0006508 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IEA
    mitochondrion GO:0005739 ISS
    focal adhesion GO:0005925 IEA
    nucleoplasm GO:0005654 IEA
 Experiment description of studies that identified LAP3 in exosomes
1
Experiment ID 213
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for LAP3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LAP3 is involved
No pathways found





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