Gene description for Ddx10
Gene name DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
Gene symbol Ddx10
Other names/aliases 4632415A01Rik
AI646054
Species Mus musculus
 Database cross references - Ddx10
ExoCarta ExoCarta_77591
Vesiclepedia VP_77591
Entrez Gene 77591
UniProt Q80Y44  
 Ddx10 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ddx10
Molecular Function
    DNA clamp loader activity GO:0003689 IEA
    RNA binding GO:0003723 IEA
    RNA helicase activity GO:0003724 IEA
    ATP binding GO:0005524 IEA
    ATP hydrolysis activity GO:0016887 IEA
    cohesin loader activity GO:0061775 IEA
    chromatin extrusion motor activity GO:0140584 IEA
    ATP-dependent H3-H4 histone complex chaperone activity GO:0140665 IEA
    ATP-dependent H2AZ histone chaperone activity GO:0140849 IEA
Biological Process
    chromatin remodeling GO:0006338 IEA
    rRNA processing GO:0006364 IBA
    anterior head development GO:0097065 IMP
    chromatin looping GO:0140588 IEA
Subcellular Localization
    nucleus GO:0005634 IBA
 Experiment description of studies that identified Ddx10 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ddx10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 3110082I17Rik  
Co-fractionation Mus musculus
2 Eed  
Affinity Capture-MS Mus musculus
3 Wdr43  
Co-fractionation Mus musculus
4 Pdcd11  
Co-fractionation Mus musculus
5 Fancd2  
Affinity Capture-MS Mus musculus
6 Dnajc21  
Co-fractionation Mus musculus
7 Esf1  
Co-fractionation Mus musculus
View the network image/svg+xml
 Pathways in which Ddx10 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here