Gene description for Pcnp
Gene name PEST proteolytic signal containing nuclear protein
Gene symbol Pcnp
Other names/aliases 1110018D06Rik
AI647035
Species Mus musculus
 Database cross references - Pcnp
ExoCarta ExoCarta_76302
Vesiclepedia VP_76302
Entrez Gene 76302
UniProt Q6P8I4  
 Pcnp identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pcnp
Biological Process
    protein ubiquitination GO:0016567 IBA
    protein ubiquitination GO:0016567 ISO
    protein ubiquitination GO:0016567 ISS
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IBA
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 ISO
    proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 ISS
Subcellular Localization
    nucleus GO:0005634 IBA
    nucleus GO:0005634 ISO
    nucleus GO:0005634 ISS
    nucleoplasm GO:0005654 ISO
    nuclear body GO:0016604 ISO
 Experiment description of studies that identified Pcnp in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pcnp
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Atxn1  
Proximity Label-MS Mus musculus
2 Atg16l1  
Affinity Capture-MS Mus musculus
3 Tmem173  
Proximity Label-MS Mus musculus
View the network image/svg+xml
 Pathways in which Pcnp is involved
No pathways found





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