Gene description for Cldn22
Gene name claudin 22
Gene symbol Cldn22
Other names/aliases 2210404A22Rik
5330431C14Rik
9530051B05Rik
Species Mus musculus
 Database cross references - Cldn22
ExoCarta ExoCarta_75677
Vesiclepedia VP_75677
Entrez Gene 75677
UniProt Q9D7U6  
 Cldn22 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Cldn22
Molecular Function
    molecular_function GO:0003674 ND
    structural molecule activity GO:0005198 IEA
    identical protein binding GO:0042802 ISS
Biological Process
    cell adhesion GO:0007155 IBA
    calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules GO:0016338 ISS
    bicellular tight junction assembly GO:0070830 IBA
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IEA
    bicellular tight junction GO:0005923 IBA
    bicellular tight junction GO:0005923 ISS
 Experiment description of studies that identified Cldn22 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Cldn22
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Cldn22 is involved
No pathways found





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