Gene description for CROCC2
Gene name ciliary rootlet coiled-coil, rootletin family member 2
Gene symbol CROCC2
Other names/aliases -
Species Homo sapiens
 Database cross references - CROCC2
ExoCarta ExoCarta_728763
Vesiclepedia VP_728763
Entrez Gene 728763
HGNC 51677
 CROCC2 identified in sEVs derived from the following tissue/cell type
Neuroblastoma cells 25944692    
 Gene ontology annotations for CROCC2
Subcellular Localization
    centrosome GO:0005813 IBA
    centriole GO:0005814 IBA
 Experiment description of studies that identified CROCC2 in sEVs
1
Experiment ID 224
MISEV standards
EM|AFM
Biophysical techniques
Alix|TSG101|CD63|CD81
Enriched markers
GOLGA2
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25944692    
Organism Homo sapiens
Experiment description Proteogenomic analysis reveals exosomes are more oncogenic than ectosomes
Authors "Keerthikumar S, Gangoda L, Liem M, Fonseka P, Atukorala I, Ozcitti C, Mechler A, Adda CG, Ang CS, Mathivanan S"
Journal name Oncotarget
Publication year 2015
Sample Neuroblastoma cells
Sample name SH-SY5Y
Isolation/purification methods Differential centrifugation
Ultracentrifugation
OptiPrep density gradient
Flotation density 1.10 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for CROCC2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CEMIP 57214
Affinity Capture-MS Homo sapiens
2 OBSL1 23363
Affinity Capture-MS Homo sapiens
3 SOX2  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CROCC2 is involved
No pathways found





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