Gene description for Taf4b
Gene name TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor
Gene symbol Taf4b
Other names/aliases 105kDa
2610524B04Rik
4932409F03Rik
AW987595
TAFII-105
TAFII105
Taf2c2
Species Mus musculus
 Database cross references - Taf4b
ExoCarta ExoCarta_72504
Entrez Gene 72504
UniProt G5E8Z2  
 Taf4b identified in exosomes derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Taf4b
Molecular Function
    protein heterodimerization activity GO:0046982 IEA
    DNA binding GO:0003677 ISO
    sequence-specific DNA binding transcription factor activity GO:0003700 IEA
    NF-kappaB binding GO:0051059 ISO
Biological Process
    oogenesis GO:0048477 IEA
    transcription from RNA polymerase II promoter GO:0006366 TAS
    DNA-templated transcription, initiation GO:0006352 IEA
    cell differentiation GO:0030154 IEA
    transcription, DNA-templated GO:0006351 IEA
    spermatogenesis GO:0007283 IEA
    regulation of transcription from RNA polymerase II promoter GO:0006357 TAS
    regulation of transcription, DNA-templated GO:0006355 IEA
Subcellular Localization
    transcription factor TFIID complex GO:0005669 IEA
    nucleolus GO:0005730 ISO
    nucleus GO:0005634 IEA
    transcription factor complex GO:0005667 TAS
    cytoplasm GO:0005737 IEA
    nucleoplasm GO:0005654 ISO
 Experiment description of studies that identified Taf4b in exosomes
1
Experiment ID 15
ISEV standards
✔
EM
EV Biophysical techniques
✘ EV Cytosolic markers
✔
CD63
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Taf4b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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