Gene description for Fbn2
Gene name fibrillin 2
Gene symbol Fbn2
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Fbn2
ExoCarta ExoCarta_689008
Vesiclepedia VP_689008
Entrez Gene 689008
 Fbn2 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Fbn2
Molecular Function
    hormone activity GO:0005179 ISO
    calcium ion binding GO:0005509 IEA
Biological Process
    placenta development GO:0001890 ISO
    signal transduction GO:0007165 IEA
    embryonic limb morphogenesis GO:0030326 ISO
    positive regulation of bone mineralization GO:0030501 ISO
    limb morphogenesis GO:0035108 ISO
    sequestering of TGFbeta in extracellular matrix GO:0035583 ISO
    glucose homeostasis GO:0042593 ISO
    camera-type eye development GO:0043010 ISO
    positive regulation of osteoblast differentiation GO:0045669 ISO
    embryonic eye morphogenesis GO:0048048 ISO
    bone trabecula formation GO:0060346 ISO
    regulation of trophoblast cell migration GO:1901163 ISO
Subcellular Localization
    microfibril GO:0001527 ISO
    extracellular region GO:0005576 ISO
    extracellular space GO:0005615 ISO
 Experiment description of studies that identified Fbn2 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Fbn2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Fbn2 is involved
No pathways found





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