Gene description for Ccdc53
Gene name coiled-coil domain containing 53
Gene symbol Ccdc53
Other names/aliases 2900091E11Rik
5730495F03Rik
Species Mus musculus
 Database cross references - Ccdc53
ExoCarta ExoCarta_67282
Vesiclepedia VP_67282
Entrez Gene 67282
UniProt Q9CR27  
 Ccdc53 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Ccdc53
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    exocytosis GO:0006887 IBA
    protein transport GO:0015031 IEA
    endosomal transport GO:0016197 NAS
    actin filament polymerization GO:0030041 IBA
    regulation of Arp2/3 complex-mediated actin nucleation GO:0034315 NAS
Subcellular Localization
    early endosome membrane GO:0031901 NAS
    WASH complex GO:0071203 IBA
    WASH complex GO:0071203 IDA
    WASH complex GO:0071203 ISO
    WASH complex GO:0071203 ISS
    WASH complex GO:0071203 NAS
 Experiment description of studies that identified Ccdc53 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Ccdc53
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ccdc53 is involved
No pathways found





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