Gene description for Tmem107
Gene name transmembrane protein 107
Gene symbol Tmem107
Other names/aliases 1110004B13Rik
2810049P21Rik
Species Mus musculus
 Database cross references - Tmem107
ExoCarta ExoCarta_66910
Vesiclepedia VP_66910
Entrez Gene 66910
UniProt Q9CPV0  
 Tmem107 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Tmem107
Molecular Function
    molecular_function GO:0003674 ND
Biological Process
    detection of nodal flow GO:0003127 IMP
    determination of left/right symmetry GO:0007368 IMP
    regulation of gene expression GO:0010468 IMP
    neural tube patterning GO:0021532 IMP
    embryonic digit morphogenesis GO:0042733 IMP
    cilium organization GO:0044782 IMP
    roof of mouth development GO:0060021 IMP
    cilium assembly GO:0060271 IMP
    cilium assembly GO:0060271 IMP
    cilium assembly GO:0060271 ISO
    cilium assembly GO:0060271 ISS
    craniofacial suture morphogenesis GO:0097094 IMP
    protein localization to ciliary transition zone GO:1904491 IBA
    protein localization to ciliary transition zone GO:1904491 IMP
    non-motile cilium assembly GO:1905515 IBA
    non-motile cilium assembly GO:1905515 IMP
    non-motile cilium assembly GO:1905515 ISO
Subcellular Localization
    membrane GO:0016020 IEA
    ciliary transition zone GO:0035869 IDA
    ciliary transition zone GO:0035869 ISO
    MKS complex GO:0036038 IBA
    MKS complex GO:0036038 ISO
    MKS complex GO:0036038 ISS
 Experiment description of studies that identified Tmem107 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Tmem107
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Tmem107 is involved
No pathways found





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