Gene description for BPGM
Gene name 2,3-bisphosphoglycerate mutase
Gene symbol BPGM
Other names/aliases DPGM
Species Homo sapiens
 Database cross references - BPGM
ExoCarta ExoCarta_669
Entrez Gene 669
HGNC 1093
MIM 613896
UniProt P07738  
 BPGM identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for BPGM
Molecular Function
    bisphosphoglycerate 2-phosphatase activity GO:0004083 IEA
    bisphosphoglycerate mutase activity GO:0004082 IEA
    phosphoglycerate mutase activity GO:0004619 IEA
Biological Process
    dephosphorylation GO:0016311 IEA
    glycolytic process GO:0006096 IEA
    carbohydrate metabolic process GO:0005975 NAS
    respiratory gaseous exchange GO:0007585 TAS
    erythrocyte development GO:0048821 IEA
Subcellular Localization
    extracellular exosome GO:0070062 IDA
 Experiment description of studies that identified BPGM in exosomes
Experiment ID 237
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for BPGM
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 GAPDH 2597
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which BPGM is involved
No pathways found

Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here