Gene description for Pam16
Gene name presequence translocase-asssociated motor 16 homolog (S. cerevisiae)
Gene symbol Pam16
Other names/aliases 2010110I09Rik
AV006767
CGI-136
Magmas
Tim16
Timm16
Species Mus musculus
 Database cross references - Pam16
ExoCarta ExoCarta_66449
Vesiclepedia VP_66449
Entrez Gene 66449
UniProt Q9CQV1  
 Pam16 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Pam16
Molecular Function
    protein binding GO:0005515 IPI
Biological Process
    ossification GO:0001503 ISO
    ossification GO:0001503 ISS
    protein import into mitochondrial matrix GO:0030150 IBA
    protein import into mitochondrial matrix GO:0030150 IEA
    DNA biosynthetic process GO:0071897 IMP
    negative regulation of apoptotic signaling pathway GO:2001234 IMP
Subcellular Localization
    PAM complex, Tim23 associated import motor GO:0001405 IDA
    cytoplasm GO:0005737 IDA
    mitochondrion GO:0005739 HDA
    mitochondrion GO:0005739 IDA
    mitochondrial inner membrane GO:0005743 HDA
    TIM23 mitochondrial import inner membrane translocase complex GO:0005744 IBA
 Experiment description of studies that identified Pam16 in sEVs
1
Experiment ID 15
MISEV standards
✔
EM
Biophysical techniques
✔
CD63
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Pam16
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Dnajc19  
Cross-Linking-MS (XL-MS) Mus musculus
View the network image/svg+xml
 Pathways in which Pam16 is involved
No pathways found





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