Gene description for Cul5
Gene name	cullin 5
Gene symbol	Cul5
Other names/aliases	-
Species	Rattus norvegicus
Database cross references - Cul5
ExoCarta	ExoCarta_64624
Vesiclepedia	VP_64624
Entrez Gene	64624
UniProt	Q9JJ31
Cul5 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Cul5

Molecular Function     ubiquitin-protein transferase activity GO:0004842 TAS     vasopressin receptor activity GO:0005000 TAS     protein-macromolecule adaptor activity GO:0030674 IBA     ubiquitin protein ligase binding GO:0031625 IBA     ubiquitin protein ligase binding GO:0031625 IEA     ubiquitin protein ligase binding GO:0031625 ISO     ubiquitin ligase complex scaffold activity GO:0160072 IEA     ubiquitin ligase complex scaffold activity GO:0160072 ISO     ubiquitin ligase complex scaffold activity GO:0160072 ISS Biological Process     protein polyubiquitination GO:0000209 TAS     ubiquitin-dependent protein catabolic process GO:0006511 IEA     G protein-coupled receptor signaling pathway GO:0007186 IEA     protein ubiquitination GO:0016567 IBA     protein ubiquitination GO:0016567 IEA     protein ubiquitination GO:0016567 ISO     cerebral cortex radially oriented cell migration GO:0021799 ISO     radial glia guided migration of Purkinje cell GO:0021942 ISO     SCF-dependent proteasomal ubiquitin-dependent protein catabolic process GO:0031146 IBA     reelin-mediated signaling pathway GO:0038026 ISO     reelin-mediated signaling pathway GO:0038026 ISS     proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 IEA     proteasome-mediated ubiquitin-dependent protein catabolic process GO:0043161 ISO     regulation of cytosolic calcium ion concentration GO:0051480 IMP     protein K11-linked ubiquitination GO:0070979 IEA     protein K11-linked ubiquitination GO:0070979 ISO     regulation of neuron migration GO:2001222 ISO     regulation of neuron migration GO:2001222 ISS Subcellular Localization     nucleus GO:0005634 IEA     nucleus GO:0005634 ISO     SCF ubiquitin ligase complex GO:0019005 IBA     cullin-RING ubiquitin ligase complex GO:0031461 IEA     Cul5-RING ubiquitin ligase complex GO:0031466 IBA     Cul5-RING ubiquitin ligase complex GO:0031466 IEA     Cul5-RING ubiquitin ligase complex GO:0031466 ISO     Cul5-RING ubiquitin ligase complex GO:0031466 ISS     Cul5-RING ubiquitin ligase complex GO:0031466 TAS     site of DNA damage GO:0090734 IEA     site of DNA damage GO:0090734 ISO     site of DNA damage GO:0090734 ISS