Gene description for Ccdc80
Gene name coiled-coil domain containing 80
Gene symbol Ccdc80
Other names/aliases CL2
Dro1
Ssg1
Species Rattus norvegicus
 Database cross references - Ccdc80
ExoCarta ExoCarta_64387
Vesiclepedia VP_64387
Entrez Gene 64387
UniProt Q6QD51  
 Ccdc80 identified in sEVs derived from the following tissue/cell type
Pancreatic cancer cells 20124479    
Pancreatic cancer cells 20124479    
 Gene ontology annotations for Ccdc80
Molecular Function
    fibronectin binding GO:0001968 ISO
    glycosaminoglycan binding GO:0005539 ISO
    heparin binding GO:0008201 ISO
Biological Process
    response to bacterium GO:0009617 ISO
    positive regulation of cell-substrate adhesion GO:0010811 IBA
    positive regulation of cell-substrate adhesion GO:0010811 ISO
    extracellular matrix organization GO:0030198 IBA
    extracellular matrix organization GO:0030198 ISO
Subcellular Localization
    extracellular region GO:0005576 IEA
    basement membrane GO:0005604 IBA
    basement membrane GO:0005604 ISO
    interstitial matrix GO:0005614 ISO
    extracellular matrix GO:0031012 ISO
 Experiment description of studies that identified Ccdc80 in sEVs
1
Experiment ID 92
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
RatRef-12 Microarray
FACS
Mass spectrometry [MALDI TOF]
2
Experiment ID 93
MISEV standards
EM
Biophysical techniques
HSP70|GAPDH|CD9|CD151
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 20124479    
Organism Rattus norvegicus
Experiment description Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation.
Authors "Nazarenko I, Rana S, Baumann A, McAlear J, Hellwig A, Trendelenburg M, Lochnit G, Preissner KT, Zoller M."
Journal name CR
Publication year 2010
Sample Pancreatic cancer cells
Sample name AS-Tspan8
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.14-1.17 g/mL
Molecules identified in the study Protein
mRNA
Methods used in the study RT-PCR
Western blotting
 Protein-protein interactions for Ccdc80
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Ccdc80 is involved
No pathways found





Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here