Gene description for AKR1A1
Gene name aldo-keto reductase family 1, member A1 (aldehyde reductase)
Gene symbol AKR1A1
Other names/aliases -
Species Bos taurus
 Database cross references - AKR1A1
ExoCarta ExoCarta_618607
Vesiclepedia VP_618607
Entrez Gene 618607
UniProt Q3ZCJ2  
 AKR1A1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
Serum 19327352    
 Gene ontology annotations for AKR1A1
Molecular Function
    aldose reductase (NADPH) activity GO:0004032 IEA
Biological Process
    aldehyde catabolic process GO:0046185 IEA
Subcellular Localization
    cytosol GO:0005829 IEA
 Experiment description of studies that identified AKR1A1 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
2
Experiment ID 187
MISEV standards
✔
EM
Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19327352    
Organism Bos taurus
Experiment description Anchorage-independent growth of breast carcinoma cells is mediated by serum exosomes.
Authors "Ochieng J, Pratap S, Khatua AK, Sakwe AM."
Journal name Exp Cell Res
Publication year 2009
Sample Serum
Sample name Normal - Fetal bovine serum
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for AKR1A1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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