Gene description for FIS1
Gene name fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae)
Gene symbol FIS1
Other names/aliases -
Species Bos taurus
 Database cross references - FIS1
ExoCarta ExoCarta_615565
Vesiclepedia VP_615565
Entrez Gene 615565
UniProt Q3T0I5  
 FIS1 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for FIS1
Molecular Function
    protein binding GO:0005515 IEA
Biological Process
    mitochondrial fission GO:0000266 IEA
    autophagy of mitochondrion GO:0000422 IEA
    peroxisome fission GO:0016559 IEA
    mitochondrial fragmentation involved in apoptotic process GO:0043653 IEA
Subcellular Localization
    mitochondrial outer membrane GO:0005741 IEA
    peroxisomal membrane GO:0005778 IEA
 Experiment description of studies that identified FIS1 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for FIS1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which FIS1 is involved
PathwayEvidenceSource
Class I peroxisomal membrane protein import IEA Reactome
Protein localization IEA Reactome





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