Gene description for CD248
Gene name CD248 molecule, endosialin
Gene symbol CD248
Other names/aliases CD164L1
TEM1
Species Homo sapiens
 Database cross references - CD248
ExoCarta ExoCarta_57124
Entrez Gene 57124
HGNC 18219
MIM 606064
UniProt Q9HCU0  
 CD248 identified in exosomes derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for CD248
Molecular Function
    extracellular matrix binding GO:0050840 IEA
    calcium ion binding GO:0005509 IEA
    carbohydrate binding GO:0030246 IEA
    molecular_function GO:0003674 ND
Biological Process
    positive regulation of cell proliferation GO:0008284 IEA
    lymph node development GO:0048535 IEA
    anatomical structure regression GO:0060033 IEA
    positive regulation of endothelial cell apoptotic process GO:2000353 IEA
    cell migration GO:0016477 IEA
    biological_process GO:0008150 ND
Subcellular Localization
    proteinaceous extracellular matrix GO:0005578 TAS
    cytoplasm GO:0005737 IEA
    extracellular exosome GO:0070062 IDA
    integral component of membrane GO:0016021 IEA
 Experiment description of studies that identified CD248 in exosomes
1
Experiment ID 126
ISEV standards
✘ EV Biophysical techniques
✔
GAPDH
EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for CD248
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which CD248 is involved
No pathways found





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