Gene description for Clec1b
Gene name C-type lectin domain family 1, member b
Gene symbol Clec1b
Other names/aliases 1810061I13Rik
Clec-2
Clec2
Species Mus musculus
 Database cross references - Clec1b
ExoCarta ExoCarta_56760
Vesiclepedia VP_56760
Entrez Gene 56760
UniProt Q9JL99  
 Clec1b identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Clec1b
Molecular Function
    transmembrane signaling receptor activity GO:0004888 IBA
    transmembrane signaling receptor activity GO:0004888 ISA
    transmembrane signaling receptor activity GO:0004888 ISO
    transmembrane signaling receptor activity GO:0004888 ISS
    carbohydrate binding GO:0030246 IEA
Biological Process
    signal transduction GO:0007165 IBA
    signal transduction GO:0007165 ISO
    signal transduction GO:0007165 ISS
    cell surface receptor signaling pathway GO:0007166 TAS
    platelet formation GO:0030220 IBA
    platelet formation GO:0030220 IGI
Subcellular Localization
    plasma membrane GO:0005886 IBA
    plasma membrane GO:0005886 IDA
    cell surface GO:0009986 IDA
 Experiment description of studies that identified Clec1b in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Clec1b
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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