Gene description for Clcf1
Gene name	cardiotrophin-like cytokine factor 1
Gene symbol	Clcf1
Other names/aliases	Bsf3 CLC
Species	Mus musculus
Database cross references - Clcf1
ExoCarta	ExoCarta_56708
Vesiclepedia	VP_56708
Entrez Gene	56708
UniProt	Q9QZM3
Clcf1 identified in sEVs derived from the following tissue/cell type
Fibroblasts	23260141

Gene ontology annotations for Clcf1

Molecular Function     signaling receptor binding GO:0005102 ISO     signaling receptor binding GO:0005102 ISS     cytokine activity GO:0005125 IDA     cytokine activity GO:0005125 ISO     ciliary neurotrophic factor receptor binding GO:0005127 ISO     ciliary neurotrophic factor receptor binding GO:0005127 ISO     ciliary neurotrophic factor receptor binding GO:0005127 ISS     ciliary neurotrophic factor receptor binding GO:0005127 TAS     protein binding GO:0005515 IPI Biological Process     positive regulation of immunoglobulin production GO:0002639 IDA     positive regulation of type 2 immune response GO:0002830 NAS     cell surface receptor signaling pathway GO:0007166 IDA     cell surface receptor signaling pathway via JAK-STAT GO:0007259 IBA     cell surface receptor signaling pathway via JAK-STAT GO:0007259 IDA     positive regulation of cell population proliferation GO:0008284 ISO     positive regulation of cell population proliferation GO:0008284 ISS     B cell differentiation GO:0030183 IDA     positive regulation of B cell proliferation GO:0030890 IBA     positive regulation of B cell proliferation GO:0030890 IDA     positive regulation of tyrosine phosphorylation of STAT protein GO:0042531 ISO     negative regulation of neuron apoptotic process GO:0043524 ISO     negative regulation of neuron apoptotic process GO:0043524 ISS     negative regulation of neuron apoptotic process GO:0043524 NAS     positive regulation of isotype switching to IgE isotypes GO:0048295 IDA     positive regulation of astrocyte differentiation GO:0048711 IDA     regulation of inflammatory response GO:0050727 NAS     positive regulation of corticotropin-releasing hormone secretion GO:0051466 TAS     regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction GO:0051896 TAS     regulation of ERK1 and ERK2 cascade GO:0070372 TAS     cell surface receptor signaling pathway via STAT GO:0097696 IDA     negative regulation of motor neuron apoptotic process GO:2000672 NAS Subcellular Localization     extracellular region GO:0005576 IBA     extracellular region GO:0005576 ISO     extracellular region GO:0005576 ISS     extracellular space GO:0005615 IEA     CRLF-CLCF1 complex GO:0097058 IBA     CRLF-CLCF1 complex GO:0097058 ISO     CRLF-CLCF1 complex GO:0097058 ISS     CRLF-CLCF1 complex GO:0097058 TAS     CNTFR-CLCF1 complex GO:0097059 IBA     CNTFR-CLCF1 complex GO:0097059 IEA     CNTFR-CLCF1 complex GO:0097059 ISO