Gene description for Anxa2
Gene name	annexin A2
Gene symbol	Anxa2
Other names/aliases	ANX2
Species	Rattus norvegicus
Database cross references - Anxa2
ExoCarta	ExoCarta_56611
Vesiclepedia	VP_56611
Entrez Gene	56611
UniProt	Q07936
Anxa2 identified in exosomes derived from the following tissue/cell type
Adipocytes	25998041
Hepatocytes	19367702
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046
Urine	20535238

Gene ontology annotations for Anxa2

Molecular Function     phosphatidylserine binding GO:0001786 IBA     protease binding GO:0002020 ISO     phospholipase inhibitor activity GO:0004859 IEA     serine-type endopeptidase inhibitor activity GO:0004867 ISO     calcium ion binding GO:0005509 IEA     calcium ion binding GO:0005509 TAS     calcium-dependent phospholipid binding GO:0005544 IBA     calcium-dependent phospholipid binding GO:0005544 IEA     calcium-dependent phospholipid binding GO:0005544 ISO     phosphatidylinositol-4,5-bisphosphate binding GO:0005546 IDA     phosphatidylinositol-4,5-bisphosphate binding GO:0005546 ISO     cytoskeletal protein binding GO:0008092 IEA     phospholipase A2 inhibitor activity GO:0019834 ISO     small GTPase binding GO:0031267 IPI     identical protein binding GO:0042802 ISO     S100 protein binding GO:0044548 ISO     bone sialoprotein binding GO:0044730 IPI     calcium-dependent protein binding GO:0048306 ISO     actin filament binding GO:0051015 TAS Biological Process     angiogenesis GO:0001525 IEA     angiogenesis GO:0001525 ISO     angiogenesis GO:0001525 ISO     membrane raft assembly GO:0001765 ISO     positive regulation of receptor recycling GO:0001921 IEA     positive regulation of receptor recycling GO:0001921 ISO     positive regulation of protein phosphorylation GO:0001934 IMP     negative regulation of receptor internalization GO:0002091 ISO     vesicle budding from membrane GO:0006900 ISO     cell adhesion GO:0007155 ISO     cell-matrix adhesion GO:0007160 IEA     cell-matrix adhesion GO:0007160 ISO     body fluid secretion GO:0007589 IMP     positive regulation of plasminogen activation GO:0010756 ISO     response to activity GO:0014823 IEA     response to activity GO:0014823 ISO     collagen fibril organization GO:0030199 IEA     collagen fibril organization GO:0030199 ISO     lung development GO:0030324 IEA     lung development GO:0030324 ISO     positive regulation of vesicle fusion GO:0031340 ISO     negative regulation of low-density lipoprotein particle receptor catabolic process GO:0032804 IEA     negative regulation of low-density lipoprotein particle receptor catabolic process GO:0032804 ISO     osteoclast development GO:0036035 ISO     fibrinolysis GO:0042730 IEA     fibrinolysis GO:0042730 ISO     mRNA transcription by RNA polymerase II GO:0042789 IEA     mRNA transcription by RNA polymerase II GO:0042789 ISO     positive regulation of vacuole organization GO:0044090 ISO     positive regulation by host of viral process GO:0044794 ISO     positive regulation of transcription by RNA polymerase II GO:0045944 IEA     positive regulation of transcription by RNA polymerase II GO:0045944 ISO     positive regulation of fibroblast proliferation GO:0048146 IMP     regulation of neurogenesis GO:0050767 IEA     regulation of neurogenesis GO:0050767 ISO     regulation of fibrinolysis GO:0051917 TAS     protein localization to plasma membrane GO:0072659 IMP     response to thyroid hormone GO:0097066 IEP     positive regulation of viral life cycle GO:1903902 ISO     epithelial cell apoptotic process GO:1904019 IEA     epithelial cell apoptotic process GO:1904019 ISO     positive regulation of low-density lipoprotein particle clearance GO:1905581 IEA     positive regulation of low-density lipoprotein particle clearance GO:1905581 ISO     positive regulation of low-density lipoprotein receptor activity GO:1905599 ISO     positive regulation of receptor-mediated endocytosis involved in cholesterol transport GO:1905602 IBA     positive regulation of receptor-mediated endocytosis involved in cholesterol transport GO:1905602 IEA     positive regulation of receptor-mediated endocytosis involved in cholesterol transport GO:1905602 ISO Subcellular Localization     cornified envelope GO:0001533 IEA     cornified envelope GO:0001533 ISO     ruffle GO:0001726 IDA     extracellular region GO:0005576 IEA     basement membrane GO:0005604 IEA     nucleus GO:0005634 IBA     cytoplasm GO:0005737 IBA     cytoplasm GO:0005737 ISO     lysosomal membrane GO:0005765 ISO     endosome GO:0005768 ISO     early endosome GO:0005769 IEA     early endosome GO:0005769 ISO     lipid droplet GO:0005811 ISO     cytosol GO:0005829 IDA     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     plasma membrane GO:0005886 IBA     plasma membrane GO:0005886 IDA     plasma membrane GO:0005886 ISO     cell cortex GO:0005938 IDA     cell surface GO:0009986 IEA     cell surface GO:0009986 ISO     vesicle membrane GO:0012506 IBA     membrane GO:0016020 IDA     basolateral plasma membrane GO:0016323 IEA     basolateral plasma membrane GO:0016323 ISO     midbody GO:0030496 ISO     late endosome membrane GO:0031902 ISO     vesicle GO:0031982 IDA     protein-containing complex GO:0032991 IDA     myelin sheath adaxonal region GO:0035749 IEA     myelin sheath adaxonal region GO:0035749 ISO     sarcolemma GO:0042383 IEA     sarcolemma GO:0042383 ISO     melanosome GO:0042470 IEA     Schmidt-Lanterman incisure GO:0043220 IEA     Schmidt-Lanterman incisure GO:0043220 ISO     macropinosome GO:0044354 IDA     membrane raft GO:0045121 IDA     membrane raft GO:0045121 ISO     perinuclear region of cytoplasm GO:0048471 IDA     extracellular exosome GO:0070062 ISO     exocytic vesicle GO:0070382 ISO     RNA polymerase II transcription regulator complex GO:0090575 IEA     RNA polymerase II transcription regulator complex GO:0090575 ISO     plasma membrane protein complex GO:0098797 IEA     plasma membrane protein complex GO:0098797 ISO     AnxA2-p11 complex GO:1990665 ISO     PCSK9-AnxA2 complex GO:1990667 ISO