Gene description for Morf4l2
Gene name mortality factor 4 like 2
Gene symbol Morf4l2
Other names/aliases 2410017O14Rik
Mrgx
Sid393p
mKIAA0026
Species Mus musculus
 Database cross references - Morf4l2
ExoCarta ExoCarta_56397
Vesiclepedia VP_56397
Entrez Gene 56397
UniProt Q9R0Q4  
 Morf4l2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Morf4l2
Biological Process
    DNA repair GO:0006281 IEA
    chromatin organization GO:0006325 IEA
    regulation of apoptotic process GO:0042981 NAS
    positive regulation of DNA-templated transcription GO:0045893 NAS
    positive regulation of transcription by RNA polymerase II GO:0045944 IEA
    positive regulation of striated muscle cell differentiation GO:0051155 IEA
    regulation of cell cycle GO:0051726 ISO
    positive regulation of double-strand break repair via homologous recombination GO:1905168 ISO
    regulation of double-strand break repair GO:2000779 NAS
Subcellular Localization
    nucleosome GO:0000786 ISO
    nucleoplasm GO:0005654 IEA
    nucleoplasm GO:0005654 ISO
    nucleolus GO:0005730 IEA
    nucleolus GO:0005730 ISO
    plasma membrane GO:0005886 IEA
    plasma membrane GO:0005886 ISO
    NuA4 histone acetyltransferase complex GO:0035267 IBA
    NuA4 histone acetyltransferase complex GO:0035267 ISO
 Experiment description of studies that identified Morf4l2 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule mrna
Identification method Microarray
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Morf4l2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Kctd13  
Affinity Capture-MS Mus musculus
View the network image/svg+xml
 Pathways in which Morf4l2 is involved
No pathways found





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