Gene description for Gltp
Gene name glycolipid transfer protein
Gene symbol Gltp
Other names/aliases 1110001F24Rik
C76925
C77564
Species Mus musculus
 Database cross references - Gltp
ExoCarta ExoCarta_56356
Vesiclepedia VP_56356
Entrez Gene 56356
UniProt Q9JL62  
 Gltp identified in sEVs derived from the following tissue/cell type
Oligodendrocytes 21136642    
 Gene ontology annotations for Gltp
Molecular Function
    lipid binding GO:0008289 ISO
    lipid binding GO:0008289 ISS
    identical protein binding GO:0042802 IEA
    identical protein binding GO:0042802 ISO
    glycolipid binding GO:0051861 ISO
    glycolipid binding GO:0051861 ISS
    lipid transfer activity GO:0120013 ISO
    lipid transfer activity GO:0120013 ISS
    ceramide 1-phosphate binding GO:1902387 IBA
    ceramide 1-phosphate transfer activity GO:1902388 IBA
Biological Process
    ceramide transport GO:0035627 IBA
    response to immobilization stress GO:0035902 IEA
    intermembrane lipid transfer GO:0120009 IBA
    intermembrane lipid transfer GO:0120009 ISO
    intermembrane lipid transfer GO:0120009 ISS
Subcellular Localization
    cytosol GO:0005829 IBA
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
 Experiment description of studies that identified Gltp in sEVs
1
Experiment ID 33
MISEV standards
EM|IEM
Biophysical techniques
Alix|TSG101
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 21136642    
Organism Mus musculus
Experiment description Oligodendrocytes secrete exosomes containing major myelin and stress-protective proteins: Trophic support for axons?
Authors "Kramer-Albers EM, Bretz N, Tenzer S, Winterstein C, Mobius W, Berger H, Nave KA, Schild H, Trotter J"
Journal name PROTEOMICS_CL
Publication year 2007
Sample Oligodendrocytes
Sample name Oligodendrocytes
Oli-neu
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.10-1.14 g/mL
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for Gltp
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gltp is involved
PathwayEvidenceSource
Glycosphingolipid transport IEA Reactome
Transport of small molecules IEA Reactome





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