Gene description for SLC7A10
Gene name solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10
Gene symbol SLC7A10
Other names/aliases ASC1
HASC-1
asc-1
Species Homo sapiens
 Database cross references - SLC7A10
ExoCarta ExoCarta_56301
Vesiclepedia VP_56301
Entrez Gene 56301
HGNC 11058
MIM 607959
UniProt Q9NS82  
 SLC7A10 identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells Unpublished / Not applicable
 Gene ontology annotations for SLC7A10
Molecular Function
    protein binding GO:0005515 IPI
    neutral L-amino acid transmembrane transporter activity GO:0015175 IBA
    neutral L-amino acid transmembrane transporter activity GO:0015175 IDA
    L-amino acid transmembrane transporter activity GO:0015179 IBA
    L-serine transmembrane transporter activity GO:0015194 TAS
Biological Process
    amino acid transport GO:0006865 TAS
    neutral amino acid transport GO:0015804 IDA
    glycine transport GO:0015816 IEA
    L-serine transport GO:0015825 IEA
    D-alanine transmembrane transport GO:0042941 IBA
    D-serine transmembrane transport GO:0042942 IBA
    positive regulation of synaptic transmission, glycinergic GO:0060094 IEA
    L-alpha-amino acid transmembrane transport GO:1902475 IEA
    negative regulation of brown fat cell differentiation GO:1903444 IEA
Subcellular Localization
    plasma membrane GO:0005886 NAS
    plasma membrane GO:0005886 TAS
    membrane GO:0016020 TAS
 Experiment description of studies that identified SLC7A10 in sEVs
1
Experiment ID 126
MISEV standards
Biophysical techniques
GAPDH
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [LTQ-FT Ultra]
PubMed ID Unpublished / Not applicable
Organism Homo sapiens
Experiment description Mesenchymal Stem Cell Exosomes: The Future MSC-based Therapy?
Authors "Ruenn Chai Lai, Ronne Wee Yeh Yeo, Soon Sim Tan, Bin Zhang, Yijun Yin, Newman Siu Kwan Sze, Andre Choo, and Sai Kiang Lim"
Journal name Mesenchymal Stem Cell Therapy
Publication year 2011
Sample Mesenchymal stem cells
Sample name huES9.E1
Isolation/purification methods HPLC
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Antobody array
Mass spectrometry
 Protein-protein interactions for SLC7A10
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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