Gene description for FAM46C
Gene name family with sequence similarity 46, member C
Gene symbol FAM46C
Other names/aliases -
Species Homo sapiens
 Database cross references - FAM46C
ExoCarta ExoCarta_54855
Entrez Gene 54855
HGNC 24712
MIM 613952
UniProt Q5VWP2  
 FAM46C identified in exosomes derived from the following tissue/cell type
Hepatocytes 26054723    
 Gene ontology annotations for FAM46C
Molecular Function
    protein binding GO:0005515 IPI
 Experiment description of studies that identified FAM46C in exosomes
Experiment ID 237
ISEV standards
EV Biophysical techniques
EV Cytosolic markers
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule mRNA
Identification method RNA Sequencing
PubMed ID 26054723    
Organism Homo sapiens
Experiment description Hepatocellular carcinoma-derived exosomes promote motility of immortalized hepatocyte through transfer of oncogenic proteins and RNAs
Authors He M, Qin H, Poon TC, Sze SC, Ding X, Co NN, Ngai SM, Chan TF, Wong N
Journal name Carcinogenesis
Publication year 2015
Sample Hepatocytes
Sample name MIHA
Isolation/purification methods Differential centrifugation
Sucrose density gradient
Flotation density 1.13-1.19 g/mL
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
RNA Sequencing
 Protein-protein interactions for FAM46C
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 DAZAP2  
Two-hybrid Homo sapiens
2 PLK4  
Two-hybrid Homo sapiens
3 AP2B1 163
Two-hybrid Homo sapiens
4 TRIP6  
Two-hybrid Homo sapiens
View the network image/svg+xml
 Pathways in which FAM46C is involved
No pathways found

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