Gene description for Aox1
Gene name aldehyde oxidase 1
Gene symbol Aox1
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Aox1
ExoCarta ExoCarta_54349
Vesiclepedia VP_54349
Entrez Gene 54349
UniProt Q9Z0U5  
 Aox1 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Aox1
Molecular Function
    aldehyde oxidase activity GO:0004031 IBA
    aldehyde oxidase activity GO:0004031 IDA
    aldehyde oxidase activity GO:0004031 IEA
    aldehyde oxidase activity GO:0004031 ISO
    aldehyde oxidase activity GO:0004031 ISS
    iron ion binding GO:0005506 IEA
    iron ion binding GO:0005506 ISO
    iron ion binding GO:0005506 ISS
    oxidoreductase activity GO:0016491 IEA
    identical protein binding GO:0042802 ISO
    protein homodimerization activity GO:0042803 IEA
    protein homodimerization activity GO:0042803 ISO
    protein homodimerization activity GO:0042803 ISS
    molybdopterin cofactor binding GO:0043546 IEA
    molybdopterin cofactor binding GO:0043546 ISO
    molybdopterin cofactor binding GO:0043546 ISS
    flavin adenine dinucleotide binding GO:0050660 ISO
    flavin adenine dinucleotide binding GO:0050660 ISS
    NAD binding GO:0051287 IEA
    2 iron, 2 sulfur cluster binding GO:0051537 IEA
    2 iron, 2 sulfur cluster binding GO:0051537 ISO
    2 iron, 2 sulfur cluster binding GO:0051537 ISS
    FAD binding GO:0071949 IEA
Biological Process
    lipid metabolic process GO:0006629 IEA
    xenobiotic metabolic process GO:0006805 IEA
    xenobiotic metabolic process GO:0006805 ISO
    xenobiotic metabolic process GO:0006805 ISS
    xenobiotic metabolic process GO:0006805 TAS
Subcellular Localization
    cytoplasm GO:0005737 IEA
    cytosol GO:0005829 IEA
    cytosol GO:0005829 ISO
    cytosol GO:0005829 ISS
 Experiment description of studies that identified Aox1 in sEVs
1
Experiment ID 35
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|CD81|CD63
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Aox1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here