Gene description for Copg2
Gene name coatomer protein complex, subunit gamma 2
Gene symbol Copg2
Other names/aliases AW227625
gamma-2-COP
Species Mus musculus
 Database cross references - Copg2
ExoCarta ExoCarta_54160
Vesiclepedia VP_54160
Entrez Gene 54160
UniProt Q9QXK3  
 Copg2 identified in sEVs derived from the following tissue/cell type
Mast cells 17486113    
 Gene ontology annotations for Copg2
Molecular Function
    structural molecule activity GO:0005198 IEA
Biological Process
    intracellular protein transport GO:0006886 IEA
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 IBA
    intra-Golgi vesicle-mediated transport GO:0006891 IBA
    intra-Golgi vesicle-mediated transport GO:0006891 IEA
    intra-Golgi vesicle-mediated transport GO:0006891 ISO
    protein secretion GO:0009306 IBA
    organelle transport along microtubule GO:0072384 IBA
Subcellular Localization
    Golgi membrane GO:0000139 IBA
    Golgi membrane GO:0000139 IDA
    endoplasmic reticulum GO:0005783 IBA
    endoplasmic reticulum-Golgi intermediate compartment GO:0005793 IBA
    cytosol GO:0005829 IEA
    COPI vesicle coat GO:0030126 IBA
    COPI vesicle coat GO:0030126 ISO
    COPI-coated vesicle GO:0030137 IDA
    growth cone GO:0030426 IDA
 Experiment description of studies that identified Copg2 in sEVs
1
Experiment ID 15
MISEV standards
EM
Biophysical techniques
CD63
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 17486113    
Organism Mus musculus
Homo sapiens
Experiment description Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells.
Authors "Valadi H, Ekstrom K, Bossios A, Sjostrand M, Lee JJ, Lotvall JO"
Journal name NCB
Publication year 2007
Sample Mast cells
Sample name MC9
Bone marrow-derived mast cells
HMC-1
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density 1.11-1.21 g/mL
Molecules identified in the study Protein
mRNA
miRNA
Methods used in the study Mass spectrometry [MALDI TOF]
Western blotting
Microarray
miRCURY LNA Array
 Protein-protein interactions for Copg2
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Atxn1  
Proximity Label-MS Mus musculus
2 ABCG1  
Affinity Capture-MS Homo sapiens
3 Foxp3  
Affinity Capture-MS Mus musculus
4 Tmem173  
Proximity Label-MS Mus musculus
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