Gene description for SEC63
Gene name SEC63 homolog (S. cerevisiae)
Gene symbol SEC63
Other names/aliases -
Species Bos taurus
 Database cross references - SEC63
ExoCarta ExoCarta_541040
Vesiclepedia VP_541040
Entrez Gene 541040
 SEC63 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for SEC63
Molecular Function
    RNA binding GO:0003723 IEA
    protein transmembrane transporter activity GO:0008320 IEA
Biological Process
    SRP-dependent cotranslational protein targeting to membrane GO:0006614 IEA
    post-translational protein targeting to endoplasmic reticulum membrane GO:0006620 IEA
Subcellular Localization
    Sec62/Sec63 complex GO:0031207 IEA
 Experiment description of studies that identified SEC63 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for SEC63
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 SEC62  
Affinity Capture-Western Bos taurus
2 SEC61G  
Affinity Capture-Western Bos taurus
3 SEC61B  
Affinity Capture-Western Bos taurus
Affinity Capture-Western Bos taurus
4 SEC61A1  
Affinity Capture-Western Bos taurus
View the network image/svg+xml
 Pathways in which SEC63 is involved
No pathways found





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