Gene description for PDE12
Gene name phosphodiesterase 12
Gene symbol PDE12
Other names/aliases 2'-PDE
Species Bos taurus
 Database cross references - PDE12
ExoCarta ExoCarta_538860
Vesiclepedia VP_538860
Entrez Gene 538860
UniProt Q08DF7  
 PDE12 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for PDE12
Molecular Function
    3'-5'-RNA exonuclease activity GO:0000175 IEA
Biological Process
    nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay GO:0000288 IEA
Subcellular Localization
    mitochondrion GO:0005739 IEA
 Experiment description of studies that identified PDE12 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for PDE12
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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