Gene description for Hpcal1
Gene name hippocalcin-like 1
Gene symbol Hpcal1
Other names/aliases NVP-3
Nvp3
VILIP3
Vnsl3
Vsnl3
Species Mus musculus
 Database cross references - Hpcal1
ExoCarta ExoCarta_53602
Vesiclepedia VP_53602
Entrez Gene 53602
UniProt P62748  
 Hpcal1 identified in sEVs derived from the following tissue/cell type
Colon cancer cells 37309723    
T-cell lymphoma cells 37309723    
 Gene ontology annotations for Hpcal1
Molecular Function
    calcium ion binding GO:0005509 IBA
    calcium ion binding GO:0005509 IEA
    protein binding GO:0005515 IPI
Biological Process
    biological_process GO:0008150 ND
    regulation of signal transduction GO:0009966 IBA
Subcellular Localization
    membrane GO:0016020 IEA
 Experiment description of studies that identified Hpcal1 in sEVs
1
Experiment ID 907
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample Colon cancer cells
Sample name C26
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
2
Experiment ID 908
MISEV standards
EM
Biophysical techniques
Tsg101|Sdcbp|Cd151|Gapdh|Lamp2|Cd81|Cd82|Cd9|Cd63|Cd80|Flot2|Tfrc|Rab35|Rab5a
Enriched markers
HSPA5
Negative markers
NTA
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 37309723    
Organism Mus musculus
Experiment description Proteomic analysis of the small extracellular vesicles and soluble secretory proteins from cachexia inducing and non-inducing cancer cells
Authors "Chitti SV, Kang T, Fonseka P, Marzan AL, Stewart S, Shahi S, Bramich K, Ang CS, Pathan M, Gummadi S, Mathivanan S."
Journal name Proteomics
Publication year 2023
Sample T-cell lymphoma cells
Sample name EL4
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectrometry
 Protein-protein interactions for Hpcal1
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 MAPT  
Reconstituted Complex Homo sapiens
2 Nphp4  
Affinity Capture-MS Mus musculus
3 Kcnma1  
Affinity Capture-MS Mus musculus
Affinity Capture-Western Mus musculus
View the network image/svg+xml
 Pathways in which Hpcal1 is involved
No pathways found





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