Gene description for IDE
Gene name insulin-degrading enzyme
Gene symbol IDE
Other names/aliases -
Species Bos taurus
 Database cross references - IDE
ExoCarta ExoCarta_523752
Vesiclepedia VP_523752
Entrez Gene 523752
UniProt Q24K02  
 IDE identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for IDE
Molecular Function
    metalloendopeptidase activity GO:0004222 IEA
    metal ion binding GO:0046872 IEA
Biological Process
    peptide catabolic process GO:0043171 IEA
    proteolysis involved in protein catabolic process GO:0051603 IEA
Subcellular Localization
    mitochondrion GO:0005739 IEA
    peroxisomal matrix GO:0005782 IEA
    cytosol GO:0005829 IEA
 Experiment description of studies that identified IDE in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for IDE
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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