Gene description for ACTN4
Gene name actinin, alpha 4
Gene symbol ACTN4
Other names/aliases -
Species Bos taurus
 Database cross references - ACTN4
ExoCarta ExoCarta_522269
Vesiclepedia VP_522269
Entrez Gene 522269
UniProt A5D7D1  
 ACTN4 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for ACTN4
Molecular Function
    calcium ion binding GO:0005509 IEA
    actin filament binding GO:0051015 IEA
Biological Process
    actin cytoskeleton organization GO:0030036 IEA
    muscle cell development GO:0055001 IEA
Subcellular Localization
    plasma membrane GO:0005886 IEA
    Z disc GO:0030018 IEA
    cell junction GO:0030054 IEA
    cortical actin cytoskeleton GO:0030864 IEA
    cell projection GO:0042995 IEA
 Experiment description of studies that identified ACTN4 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for ACTN4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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