Gene description for GAD1
Gene name glutamate decarboxylase 1 (brain, 67kDa)
Gene symbol GAD1
Other names/aliases -
Species Bos taurus
 Database cross references - GAD1
ExoCarta ExoCarta_517552
Entrez Gene 517552
UniProt Q0VCA1  
 GAD1 identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for GAD1
Molecular Function
    pyridoxal phosphate binding GO:0030170 IEA
    glutamate decarboxylase activity GO:0004351 IEA
Biological Process
    neurotransmitter biosynthetic process GO:0042136 IEA
    carboxylic acid metabolic process GO:0019752 IEA
Subcellular Localization
    intracellular GO:0005622 IEA
 Experiment description of studies that identified GAD1 in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for GAD1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which GAD1 is involved
PathwayEvidenceSource
GABA synthesis IEA Reactome





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