Gene description for CKLF
Gene name chemokine-like factor
Gene symbol CKLF
Other names/aliases C32
CKLF1
CKLF2
CKLF3
CKLF4
HSPC224
UCK-1
Species Homo sapiens
 Database cross references - CKLF
ExoCarta ExoCarta_51192
Vesiclepedia VP_51192
Entrez Gene 51192
HGNC 13253
MIM 616074
UniProt Q9UBR5  
 CKLF identified in sEVs derived from the following tissue/cell type
Mesenchymal stem cells 36408942    
 Gene ontology annotations for CKLF
Molecular Function
    protein binding GO:0005515 IPI
    chemokine activity GO:0008009 IDA
Biological Process
    signal transduction GO:0007165 IEA
    neutrophil chemotaxis GO:0030593 IDA
    secretion by cell GO:0032940 IDA
    macrophage chemotaxis GO:0048246 IDA
    lymphocyte chemotaxis GO:0048247 IDA
Subcellular Localization
    extracellular region GO:0005576 IDA
    extracellular space GO:0005615 IEA
    membrane GO:0016020 HDA
    membrane GO:0016020 IBA
    membrane GO:0016020 IDA
 Experiment description of studies that identified CKLF in sEVs
1
Experiment ID 488
MISEV standards
Biophysical techniques
Enriched markers
Negative markers
Particle analysis
Identified molecule Protein
Identification method Mass spectrometry
PubMed ID 36408942    
Organism Homo sapiens
Experiment description Quantitative proteomic analysis of exosomes from umbilical cord mesenchymal stem cells and rat bone marrow stem cells
Authors "Xu X, Yin F, Guo M, Gan G, Lin G, Wen C, Wang J, Song P, Wang J, Qi ZQ, Zhong CQ."
Journal name Proteomics
Publication year 2023
Sample Mesenchymal stem cells
Sample name UCMSC
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Western blotting
Mass spectometry
 Protein-protein interactions for CKLF
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 HOXB9  
Affinity Capture-MS Homo sapiens
Affinity Capture-MS Homo sapiens
2 APOB 338
Affinity Capture-MS Homo sapiens
3 GLIPR1  
Affinity Capture-MS Homo sapiens
View the network image/svg+xml
 Pathways in which CKLF is involved
No pathways found





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