|
Gene description for IGK |
| Gene name |
immunoglobulin kappa locus |
| Gene symbol |
IGK |
| Other names/aliases |
IGK@ |
| Species |
Homo sapiens |
Database cross references - IGK |
| ExoCarta |
ExoCarta_50802 |
| Vesiclepedia |
VP_50802 |
| Entrez Gene |
50802 |
| HGNC |
5715 |
IGK identified in sEVs derived from the following tissue/cell type |
|
Colorectal cancer cells
|
19837982
|
|
Saliva
|
19199708
|
Gene ontology annotations for IGK |
|
|
Experiment description of studies that identified IGK in sEVs |
| 1 |
| Experiment ID |
21 |
| MISEV standards |
|
✔
EM|IEM
|
Biophysical techniques |
|
✔
Alix|TSG101|HSP70|CD63
|
Enriched markers |
|
✘
|
Negative markers |
|
✘
|
Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
|
| PubMed ID |
19837982
|
| Organism |
Homo sapiens |
| Experiment description |
Proteomic and bioinformatic analysis of immunoaffinity-purified exosomes derived from the human colon tumor cell line LIM1215. |
| Authors |
"Suresh Mathivanan, Justin W.E. Lim, Bow J. Tauro, Hong Ji, Robert L. Moritz and Richard J. Simpson" |
| Journal name |
MCP
|
| Publication year |
2009 |
| Sample |
Colorectal cancer cells |
| Sample name |
LIM1215 |
| Isolation/purification methods |
Filtration Ultracentrifugation Sucrose density gradient |
| Flotation density |
1.10-1.12 g/mL
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry [Orbitrap] Western blotting |
|
|
| 2 |
| Experiment ID |
66 |
| MISEV standards |
|
✔
IEM
|
Biophysical techniques |
|
✔
TSG101|Alix|CD63|CD81
|
Enriched markers |
|
✘
|
Negative markers |
|
✘
|
Particle analysis
|
|
| Identified molecule |
protein
|
| Identification method |
Mass spectrometry
|
| PubMed ID |
19199708
|
| Organism |
Homo sapiens |
| Experiment description |
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). |
| Authors |
"Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR" |
| Journal name |
JPR
|
| Publication year |
2009 |
| Sample |
Saliva |
| Sample name |
Saliva |
| Isolation/purification methods |
Differential centrifugation |
| Flotation density |
-
|
| Molecules identified in the study |
Protein |
| Methods used in the study |
Mass spectrometry [LTQ] Western blotting Immunoelectron Microscopy |
|
|
Protein-protein interactions for IGK |
| |
Protein Interactor |
ExoCarta ID |
Identification method |
PubMed |
Species |
|
No interactions are found.
|
|
Pathways in which IGK is involved |
|
No pathways found
|
|
|