Gene description for APOA2
Gene name apolipoprotein A-II
Gene symbol APOA2
Other names/aliases -
Species Bos taurus
 Database cross references - APOA2
ExoCarta ExoCarta_505394
Vesiclepedia VP_505394
Entrez Gene 505394
UniProt P81644  
 APOA2 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for APOA2
Molecular Function
    high-density lipoprotein particle binding GO:0008035 IEA
    cholesterol binding GO:0015485 IEA
    phosphatidylcholine binding GO:0031210 IEA
    apolipoprotein receptor binding GO:0034190 IEA
    lipase inhibitor activity GO:0055102 IEA
    high-density lipoprotein particle receptor binding GO:0070653 IEA
Biological Process
    cholesterol metabolic process GO:0008203 IEA
    cholesterol transport GO:0030301 IEA
    triglyceride-rich lipoprotein particle remodeling GO:0034370 IEA
    low-density lipoprotein particle remodeling GO:0034374 IEA
    high-density lipoprotein particle remodeling GO:0034375 IEA
    high-density lipoprotein particle assembly GO:0034380 IEA
    lipoprotein metabolic process GO:0042157 IEA
    cholesterol homeostasis GO:0042632 IEA
    negative regulation of lipase activity GO:0060192 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    very-low-density lipoprotein particle GO:0034361 IEA
    spherical high-density lipoprotein particle GO:0034366 IEA
    chylomicron GO:0042627 IEA
    blood microparticle GO:0072562 IEA
 Experiment description of studies that identified APOA2 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for APOA2
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here