Gene description for Rab43
Gene name RAB43, member RAS oncogene family
Gene symbol Rab43
Other names/aliases -
Species Rattus norvegicus
 Database cross references - Rab43
ExoCarta ExoCarta_500249
Vesiclepedia VP_500249
Entrez Gene 500249
UniProt Q53B90  
 Rab43 identified in sEVs derived from the following tissue/cell type
Hepatocytes 19367702    
 Gene ontology annotations for Rab43
Molecular Function
    GTPase activity GO:0003924 IBA
    GTPase activity GO:0003924 IEA
    GTPase activity GO:0003924 ISO
    GTPase activity GO:0003924 ISS
    GTP binding GO:0005525 IEA
Biological Process
    autophagosome assembly GO:0000045 IBA
    intracellular protein transport GO:0006886 IBA
    Golgi organization GO:0007030 ISO
    Golgi organization GO:0007030 ISS
    virion assembly GO:0019068 IEA
    retrograde transport, plasma membrane to Golgi GO:0035526 ISO
    retrograde transport, plasma membrane to Golgi GO:0035526 ISS
    cellular response to type II interferon GO:0071346 ISO
    phagosome maturation GO:0090382 ISO
    phagosome maturation GO:0090382 ISS
Subcellular Localization
    Golgi apparatus GO:0005794 ISO
    Golgi apparatus GO:0005794 ISS
    endomembrane system GO:0012505 IBA
    phagocytic vesicle membrane GO:0030670 IEA
    synaptic vesicle membrane GO:0030672 IEA
    phagocytic vesicle GO:0045335 ISO
    phagocytic vesicle GO:0045335 ISS
 Experiment description of studies that identified Rab43 in sEVs
1
Experiment ID 35
MISEV standards
✔
CEM
Biophysical techniques
✔
TSG101|Alix|CD81|CD63
Enriched markers
✔
HSPA5
Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19367702    
Organism Rattus norvegicus
Experiment description Characterization and Comprehensive Proteome Profiling of Exosomes Secreted by Hepatocytes.
Authors "Conde-Vancells J, Rodriguez-Suarez E, Embade N, Gil D, Matthiesen R, Valle M, Elortza F, Lu SC, Mato JM, Falcon-Perez JM"
Journal name JPR
Publication year 2008
Sample Hepatocytes
Sample name Hepatocytes
Isolation/purification methods Differential centrifugation
Filtration
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [QTOF]
Western blotting
 Protein-protein interactions for Rab43
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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