Gene description for FXYD2
Gene name	FXYD domain containing ion transport regulator 2
Gene symbol	FXYD2
Other names/aliases	ATP1G1 HOMG2
Species	Homo sapiens
Database cross references - FXYD2
ExoCarta	ExoCarta_486
Vesiclepedia	VP_486
Entrez Gene	486
HGNC	4026
MIM	601814
UniProt	P54710
FXYD2 identified in sEVs derived from the following tissue/cell type
Thymus	23844026
Urine	15326289
Urine	19056867

Gene ontology annotations for FXYD2

Molecular Function     ATPase activator activity GO:0001671 ISS     protein binding GO:0005515 IPI     sodium channel regulator activity GO:0017080 IBA     protein-macromolecule adaptor activity GO:0030674 ISS Biological Process     intracellular sodium ion homeostasis GO:0006883 ISO     establishment or maintenance of transmembrane electrochemical gradient GO:0010248 NAS     intracellular potassium ion homeostasis GO:0030007 ISO     sodium ion export across plasma membrane GO:0036376 ISO     sodium ion export across plasma membrane GO:0036376 ISS     transmembrane transport GO:0055085 ISS     proton transmembrane transport GO:1902600 NAS     positive regulation of sodium ion export across plasma membrane GO:1903278 IBA     positive regulation of P-type sodium:potassium-exchanging transporter activity GO:1903408 ISS     potassium ion import across plasma membrane GO:1990573 ISO     potassium ion import across plasma membrane GO:1990573 ISS Subcellular Localization     plasma membrane GO:0005886 TAS     sodium:potassium-exchanging ATPase complex GO:0005890 IPI     sodium:potassium-exchanging ATPase complex GO:0005890 ISS     extracellular exosome GO:0070062 HDA