Gene description for Men
Gene name Malic enzyme
Gene symbol Men
Other names/aliases CG10120
DmelCG10120
MDH
ME
MEN
Mdh-NADP
Me
anon-WO0118547.278
mem
men
Species Drosophila melanogaster
 Database cross references - Men
ExoCarta ExoCarta_47173
Entrez Gene 47173
 Men identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Men
Molecular Function
    malate dehydrogenase (decarboxylating) (NADP+) activity GO:0004473 ISS
    NAD binding GO:0051287 IEA
    malate dehydrogenase (decarboxylating) (NAD+) activity GO:0004471 IEA
Biological Process
    determination of adult lifespan GO:0008340 IMP
    malate metabolic process GO:0006108 IMP
    sleep GO:0030431 IMP
    regulation of cell death GO:0010941 IMP
    oxidation-reduction process GO:0055114 IEA
Subcellular Localization
    cytosol GO:0005829 IDA
 Experiment description of studies that identified Men in exosomes
1
Experiment ID 202
ISEV standards
IEM
EV Biophysical techniques
TSG10|RAB35
EV Cytosolic markers
FLOT2
EV Membrane markers
EV Negative markers
EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Men
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Men is involved
No pathways found





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