Gene description for Krt10
Gene name keratin 10, type I
Gene symbol Krt10
Other names/aliases Ka10
Species Rattus norvegicus
 Database cross references - Krt10
ExoCarta ExoCarta_450225
Vesiclepedia VP_450225
Entrez Gene 450225
UniProt Q6IFW6  
 Krt10 identified in sEVs derived from the following tissue/cell type
Adipocytes 25998041    
 Gene ontology annotations for Krt10
Molecular Function
    cytoskeletal protein binding GO:0008092 ISO
    structural constituent of skin epidermis GO:0030280 IBA
    structural constituent of skin epidermis GO:0030280 IEA
    structural constituent of skin epidermis GO:0030280 ISO
    protein heterodimerization activity GO:0046982 IEA
    protein heterodimerization activity GO:0046982 ISO
    protein heterodimerization activity GO:0046982 ISS
Biological Process
    keratinocyte development GO:0003334 ISO
    biological_process GO:0008150 ND
    epidermis development GO:0008544 IBA
    epidermis development GO:0008544 ISO
    peptide cross-linking GO:0018149 ISO
    keratinocyte differentiation GO:0030216 IEA
    keratinocyte differentiation GO:0030216 ISO
    keratinocyte differentiation GO:0030216 ISO
    epithelial cell differentiation GO:0030855 IBA
    intermediate filament organization GO:0045109 IBA
    intermediate filament organization GO:0045109 ISO
    positive regulation of epidermis development GO:0045684 ISO
    positive regulation of epidermis development GO:0045684 ISS
    stem cell differentiation GO:0048863 ISO
    protein heterotetramerization GO:0051290 IEA
    protein heterotetramerization GO:0051290 ISO
    protein heterotetramerization GO:0051290 ISS
    cellular response to calcium ion GO:0071277 ISO
Subcellular Localization
    cornified envelope GO:0001533 IEA
    cornified envelope GO:0001533 ISO
    cornified envelope GO:0001533 ISO
    extracellular region GO:0005576 IEA
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    cytoplasm GO:0005737 ISS
    cytoskeleton GO:0005856 IBA
    cell surface GO:0009986 IEA
    keratin filament GO:0045095 IBA
    keratin filament GO:0045095 IEA
    keratin filament GO:0045095 ISO
 Experiment description of studies that identified Krt10 in sEVs
1
Experiment ID 225
MISEV standards
✔
EM
Biophysical techniques
✔
GAPDH|CD63
Enriched markers
✘ Negative markers
✔
NTA
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 25998041    
Organism Rattus norvegicus
Experiment description Proteomic Analysis of Extracellular Vesicles Released by Adipocytes of Otsuka Long-Evans Tokushima Fatty (OLETF) Rats.
Authors "Lee JE, Moon PG, Lee IK, Baek MC"
Journal name Protein J
Publication year 2015
Sample Adipocytes
Sample name Adipocytes
Isolation/purification methods Differential centrifugation
Filtration
Ultracentrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
Western blotting
 Protein-protein interactions for Krt10
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Sumo3  
Affinity Capture-MS Rattus norvegicus
View the network image/svg+xml
 Pathways in which Krt10 is involved
No pathways found





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