Gene description for cindr
Gene name CIN85 and CD2AP orthologue
Gene symbol cindr
Other names/aliases BcDNA:GH03163
CD2AP
CG11316
CG1408
CG31012
Cindr
DmelCG31012
Species Drosophila melanogaster
 Database cross references - cindr
ExoCarta ExoCarta_43654
Vesiclepedia VP_43654
Entrez Gene 43654
 cindr identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for cindr
Molecular Function
    SH3 domain binding GO:0017124 IDA
    GTPase activating protein binding GO:0032794 IPI
    cell adhesion molecule binding GO:0050839 IPI
Biological Process
    compound eye morphogenesis GO:0001745 IGI
    compound eye morphogenesis GO:0001745 IMP
    actin filament organization GO:0007015 IMP
    border follicle cell migration GO:0007298 IMP
    regulation of cytokinesis GO:0032465 IMP
    adherens junction assembly GO:0034333 IMP
    intercellular bridge organization GO:0043063 IMP
    positive regulation of receptor-mediated endocytosis GO:0048260 IGI
    compound eye development GO:0048749 IMP
Subcellular Localization
    midbody GO:0030496 IDA
    neuromuscular junction GO:0031594 IDA
    cleavage furrow GO:0032154 IDA
    fusome GO:0045169 IDA
    intercellular bridge GO:0045171 IDA
    apical cortex GO:0045179 IDA
    presynapse GO:0098793 IDA
 Experiment description of studies that identified cindr in sEVs
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for cindr
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Tab2  
Affinity Capture-MS Drosophila melanogaster
2 scra  
Affinity Capture-Western Drosophila melanogaster
3 Exo84  
Two-hybrid Drosophila melanogaster
4 Tak1  
Affinity Capture-MS Drosophila melanogaster
5 key  
Affinity Capture-MS Drosophila melanogaster
6 CG31038  
Two-hybrid Drosophila melanogaster
7 rdx  
Two-hybrid Drosophila melanogaster
8 CG8927  
Two-hybrid Drosophila melanogaster
9 CG3353  
Two-hybrid Drosophila melanogaster
10 tsh  
Affinity Capture-MS Drosophila melanogaster
11 bsk  
Two-hybrid Drosophila melanogaster
Two-hybrid Drosophila melanogaster
12 CG1339  
Two-hybrid Drosophila melanogaster
13 imd  
Affinity Capture-MS Drosophila melanogaster
14 Spx  
Two-hybrid Drosophila melanogaster
15 hb  
Affinity Capture-MS Drosophila melanogaster
16 Rel  
Affinity Capture-MS Drosophila melanogaster
17 PGRP-LE  
Affinity Capture-MS Drosophila melanogaster
18 en  
Affinity Capture-MS Drosophila melanogaster
19 Iap2  
Affinity Capture-MS Drosophila melanogaster
20 CG18748  
Affinity Capture-MS Drosophila melanogaster
21 ird5  
Affinity Capture-MS Drosophila melanogaster
View the network image/svg+xml
 Pathways in which cindr is involved
No pathways found





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