Gene description for T-cp1
Gene name Tcp1-like
Gene symbol T-cp1
Other names/aliases BEST:GH05123
CCT1
CG5374
DmelCG5374
T-CP1
T-cpl
TCP-1alpha
TCP1alpha
TCPA_DROME
Tcp-1
Tcp1
Tcp1-alpha
gh05123
Species Drosophila melanogaster
 Database cross references - T-cp1
ExoCarta ExoCarta_42649
Entrez Gene 42649
UniProt P12613  
 T-cp1 identified in exosomes derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for T-cp1
Molecular Function
    unfolded protein binding GO:0051082 ISS
    hydrogen-exporting ATPase activity, phosphorylative mechanism GO:0008553 NAS
    ATP binding GO:0005524 NAS
Biological Process
    phagocytosis GO:0006909 IMP
    protein folding GO:0006457 NAS
    mitotic spindle assembly GO:0090307 IMP
    mitotic spindle organization GO:0007052 IMP
Subcellular Localization
    cytosol GO:0005829 IDA
    microtubule associated complex GO:0005875 IDA
    mitochondrial proton-transporting ATP synthase complex GO:0005753 NAS
    chaperonin-containing T-complex GO:0005832 ISS
 Experiment description of studies that identified T-cp1 in exosomes
1
Experiment ID 202
ISEV standards
✔
IEM
EV Biophysical techniques
✔
TSG10|RAB35
EV Cytosolic markers
✔
FLOT2
EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP.
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for T-cp1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here