Gene description for APOC3
Gene name apolipoprotein C-III
Gene symbol APOC3
Other names/aliases -
Species Bos taurus
 Database cross references - APOC3
ExoCarta ExoCarta_408009
Vesiclepedia VP_408009
Entrez Gene 408009
UniProt P19035  
 APOC3 identified in sEVs derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for APOC3
Molecular Function
    phospholipid binding GO:0005543 IEA
    lipase inhibitor activity GO:0055102 IEA
    high-density lipoprotein particle receptor binding GO:0070653 IEA
Biological Process
    lipid transport GO:0006869 IEA
    negative regulation of triglyceride catabolic process GO:0010897 IEA
    negative regulation of very-low-density lipoprotein particle clearance GO:0010916 IEA
    negative regulation of high-density lipoprotein particle clearance GO:0010987 IEA
    negative regulation of low-density lipoprotein particle clearance GO:0010989 IEA
    lipoprotein metabolic process GO:0042157 IEA
    cholesterol homeostasis GO:0042632 IEA
    negative regulation of lipoprotein lipase activity GO:0051005 IEA
    triglyceride homeostasis GO:0070328 IEA
Subcellular Localization
    extracellular region GO:0005576 IEA
    very-low-density lipoprotein particle GO:0034361 IEA
    intermediate-density lipoprotein particle GO:0034363 IEA
    spherical high-density lipoprotein particle GO:0034366 IEA
    chylomicron GO:0042627 IEA
 Experiment description of studies that identified APOC3 in sEVs
1
Experiment ID 213
MISEV standards
✘ Biophysical techniques
✘ Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description "Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis."
Authors "Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD."
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for APOC3
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



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