Gene description for LRRC26
Gene name leucine rich repeat containing 26
Gene symbol LRRC26
Other names/aliases CAPC
bA350O14.10
Species Homo sapiens
 Database cross references - LRRC26
ExoCarta ExoCarta_389816
Vesiclepedia VP_389816
Entrez Gene 389816
HGNC 31409
MIM 613505
UniProt Q2I0M4  
 LRRC26 identified in sEVs derived from the following tissue/cell type
Saliva 19199708    
 Gene ontology annotations for LRRC26
Molecular Function
    voltage-gated potassium channel activity GO:0005249 IBA
    voltage-gated potassium channel activity GO:0005249 IDA
    protein binding GO:0005515 IPI
    potassium channel regulator activity GO:0015459 IDA
    transmembrane transporter binding GO:0044325 IBA
    transmembrane transporter binding GO:0044325 IPI
    potassium channel activator activity GO:0099104 IBA
    potassium channel activator activity GO:0099104 IDA
Biological Process
    potassium ion transmembrane transport GO:0071805 IDA
    positive regulation of voltage-gated potassium channel activity GO:1903818 IDA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    cytoskeleton GO:0005856 IEA
    plasma membrane GO:0005886 IDA
    voltage-gated potassium channel complex GO:0008076 IBA
    voltage-gated potassium channel complex GO:0008076 IDA
    extracellular exosome GO:0070062 HDA
 Experiment description of studies that identified LRRC26 in sEVs
1
Experiment ID 66
MISEV standards
IEM
Biophysical techniques
TSG101|Alix|CD63|CD81
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 19199708    
Organism Homo sapiens
Experiment description Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Authors "Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR"
Journal name JPR
Publication year 2009
Sample Saliva
Sample name Saliva
Isolation/purification methods Differential centrifugation
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry [LTQ]
Western blotting
Immunoelectron Microscopy
 Protein-protein interactions for LRRC26
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which LRRC26 is involved
No pathways found





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