Gene description for Trappc4
Gene name trafficking protein particle complex 4
Gene symbol Trappc4
Other names/aliases Sbdn
Species Rattus norvegicus
 Database cross references - Trappc4
ExoCarta ExoCarta_367073
Vesiclepedia VP_367073
Entrez Gene 367073
UniProt Q69BT7  
 Trappc4 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Trappc4
Biological Process
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 IBA
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 IEA
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 ISO
    endoplasmic reticulum to Golgi vesicle-mediated transport GO:0006888 ISS
    autophagy GO:0006914 IEA
    autophagy GO:0006914 ISO
    autophagy GO:0006914 ISS
    dendrite development GO:0016358 IEA
    dendrite development GO:0016358 ISO
Subcellular Localization
    Golgi membrane GO:0000139 IEA
    endoplasmic reticulum GO:0005783 IEA
    Golgi apparatus GO:0005794 IEA
    Golgi stack GO:0005795 IEA
    Golgi stack GO:0005795 ISO
    synaptic vesicle GO:0008021 IEA
    synaptic vesicle GO:0008021 ISO
    TRAPP complex GO:0030008 IBA
    TRAPP complex GO:0030008 IEA
    TRAPP complex GO:0030008 ISO
    TRAPP complex GO:0030008 ISS
    dendrite GO:0030425 IEA
    dendrite GO:0030425 ISO
    synapse GO:0045202 ISO
    presynaptic active zone GO:0048786 IEA
    presynaptic active zone GO:0048786 ISO
    postsynaptic density membrane GO:0098839 IEA
    postsynaptic density membrane GO:0098839 ISO
 Experiment description of studies that identified Trappc4 in sEVs
1
Experiment ID 96
MISEV standards
✔
EM
Biophysical techniques
✔
TSG101|HSP90|HSC70|MHCI
Enriched markers
✘ Negative markers
✘ Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D2 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.16-1.21 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Trappc4
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here