Gene description for Gpcpd1
Gene name glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
Gene symbol Gpcpd1
Other names/aliases Gde5
Prei4
RGD735140
Species Rattus norvegicus
 Database cross references - Gpcpd1
ExoCarta ExoCarta_362219
Vesiclepedia VP_362219
Entrez Gene 362219
UniProt Q80VJ4  
 Gpcpd1 identified in sEVs derived from the following tissue/cell type
Reticulocytes 21828046    
 Gene ontology annotations for Gpcpd1
Molecular Function
    phosphoric diester hydrolase activity GO:0008081 IEA
    glycerophosphocholine phosphodiesterase activity GO:0047389 IBA
    glycerophosphocholine phosphodiesterase activity GO:0047389 IEA
    glycerophosphocholine phosphodiesterase activity GO:0047389 ISO
    starch binding GO:2001070 IEA
Biological Process
    lipid metabolic process GO:0006629 IEA
    skeletal muscle tissue development GO:0007519 IEA
    skeletal muscle tissue development GO:0007519 ISO
    glycerophospholipid catabolic process GO:0046475 IBA
Subcellular Localization
    cytoplasm GO:0005737 IEA
    cytoplasm GO:0005737 ISO
    cytosol GO:0005829 IEA
 Experiment description of studies that identified Gpcpd1 in sEVs
1
Experiment ID 98
MISEV standards
EM
Biophysical techniques
TSG101|HSP90|HSC70|MHCI
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry [Orbitrap]
PubMed ID 21828046    
Organism Rattus norvegicus
Experiment description The proteo-lipidic composition of exosomes changes during reticulocyte maturation.
Authors "Carayon K, Chaoui K, Ronzier E, Lazar I, Bertrand-Michel J, Roques V, Balor S, Terce F, Lopez A, Salome L, Joly E."
Journal name JBC
Publication year 2011
Sample Reticulocytes
Sample name Reticulocytes - D7 Rep 2
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Sucrose density gradient
Flotation density 1.13-1.25 g/mL
Molecules identified in the study Protein
Lipids
Methods used in the study Mass spectrometry [QSTAR]
Mass spectrometry [Orbitrap]
Western blotting
 Protein-protein interactions for Gpcpd1
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which Gpcpd1 is involved
No pathways found





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