Gene description for Usp7
Gene name	ubiquitin specific peptidase 7 (herpes virus-associated)
Gene symbol	Usp7
Other names/aliases	Hausp
Species	Rattus norvegicus
Database cross references - Usp7
ExoCarta	ExoCarta_360471
Vesiclepedia	VP_360471
Entrez Gene	360471
UniProt	Q4VSI4
Usp7 identified in sEVs derived from the following tissue/cell type
Reticulocytes	21828046
Reticulocytes	21828046
Reticulocytes	21828046

Gene ontology annotations for Usp7

Molecular Function     p53 binding GO:0002039 IEA     p53 binding GO:0002039 ISO     cysteine-type endopeptidase activity GO:0004197 IEA     cysteine-type endopeptidase activity GO:0004197 ISO     cysteine-type endopeptidase activity GO:0004197 ISS     cysteine-type deubiquitinase activity GO:0004843 IBA     cysteine-type deubiquitinase activity GO:0004843 IDA     cysteine-type deubiquitinase activity GO:0004843 IEA     cysteine-type deubiquitinase activity GO:0004843 ISO     cysteine-type deubiquitinase activity GO:0004843 ISS     identical protein binding GO:0042802 IPI     deubiquitinase activity GO:0101005 ISO     deubiquitinase activity GO:0101005 ISS     K48-linked deubiquitinase activity GO:1990380 IEA     K48-linked deubiquitinase activity GO:1990380 ISO     K48-linked deubiquitinase activity GO:1990380 ISS Biological Process     transcription-coupled nucleotide-excision repair GO:0006283 IEA     transcription-coupled nucleotide-excision repair GO:0006283 ISO     transcription-coupled nucleotide-excision repair GO:0006283 ISS     DNA alkylation repair GO:0006307 IEA     DNA alkylation repair GO:0006307 ISO     DNA alkylation repair GO:0006307 ISS     proteolysis GO:0006508 IEA     protein deubiquitination GO:0016579 IDA     protein deubiquitination GO:0016579 IEA     protein deubiquitination GO:0016579 ISO     protein deubiquitination GO:0016579 ISS     regulation of protein stability GO:0031647 IBA     regulation of protein stability GO:0031647 IDA     regulation of protein stability GO:0031647 ISO     negative regulation of NF-kappaB transcription factor activity GO:0032088 ISO     negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435 IEA     negative regulation of proteasomal ubiquitin-dependent protein catabolic process GO:0032435 ISO     monoubiquitinated protein deubiquitination GO:0035520 IEA     monoubiquitinated protein deubiquitination GO:0035520 ISO     regulation of circadian rhythm GO:0042752 IEA     regulation of circadian rhythm GO:0042752 ISO     regulation of circadian rhythm GO:0042752 ISS     positive regulation of apoptotic process GO:0043065 IDA     negative regulation of gene expression via chromosomal CpG island methylation GO:0044027 IEA     negative regulation of gene expression via chromosomal CpG island methylation GO:0044027 ISO     negative regulation of gene expression via chromosomal CpG island methylation GO:0044027 ISS     negative regulation of gluconeogenesis GO:0045721 IEA     negative regulation of gluconeogenesis GO:0045721 ISO     negative regulation of gluconeogenesis GO:0045721 ISS     rhythmic process GO:0048511 IEA     protein stabilization GO:0050821 IEA     protein stabilization GO:0050821 ISO     protein stabilization GO:0050821 ISS     regulation of DNA-binding transcription factor activity GO:0051090 ISO     regulation of DNA-binding transcription factor activity GO:0051090 ISS     regulation of establishment of protein localization to telomere GO:0070203 IEA     regulation of establishment of protein localization to telomere GO:0070203 ISO     symbiont-mediated disruption of host cell PML body GO:0075342 IEA     symbiont-mediated disruption of host cell PML body GO:0075342 ISO     transcription elongation-coupled chromatin remodeling GO:0140673 ISO     negative regulation of TORC1 signaling GO:1904262 IEA     negative regulation of TORC1 signaling GO:1904262 ISO     regulation of retrograde transport, endosome to Golgi GO:1905279 IEA     regulation of retrograde transport, endosome to Golgi GO:1905279 ISO Subcellular Localization     XY body GO:0001741 ISO     nucleus GO:0005634 IBA     nucleus GO:0005634 ISO     nucleus GO:0005634 ISS     cytoplasm GO:0005737 ISO     cytosol GO:0005829 IBA     cytosol GO:0005829 IEA     cytosol GO:0005829 ISO     PML body GO:0016605 IEA     PML body GO:0016605 ISO     protein-containing complex GO:0032991 IEA     protein-containing complex GO:0032991 ISO