Gene description for Pgi
Gene name Phosphoglucose isomerase
Gene symbol Pgi
Other names/aliases CG8251
DmelCG8251
GPI
Gpi
PGI
pgi
Species Drosophila melanogaster
 Database cross references - Pgi
ExoCarta ExoCarta_35886
Vesiclepedia VP_35886
Entrez Gene 35886
UniProt P52029  
 Pgi identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for Pgi
Molecular Function
    glucose-6-phosphate isomerase activity GO:0004347 IDA
    glucose-6-phosphate isomerase activity GO:0004347 IMP
Biological Process
    fructose 6-phosphate metabolic process GO:0006002 IDA
    glucose homeostasis GO:0042593 IMP
    glucose 6-phosphate metabolic process GO:0051156 IDA
    canonical glycolysis GO:0061621 IMP
Subcellular Localization
    cytosol GO:0005829 IDA
 Experiment description of studies that identified Pgi in sEVs
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for Pgi
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 Hr46  
Affinity Capture-MS Drosophila melanogaster
2 ovo  
Affinity Capture-MS Drosophila melanogaster
3 CoVIb  
Two-hybrid Drosophila melanogaster
4 eIF4G2  
Two-hybrid Drosophila melanogaster
5 Src64B  
Two-hybrid Drosophila melanogaster
6 Tom20  
Proximity Label-MS Drosophila melanogaster
View the network image/svg+xml



Perform bioinformatics analysis of your extracellular vesicle data set using FunRich, a open access standalone tool. NEW UPDATED VERSION OF FunRich available for download (12/09/2016) from here