Gene description for CG6523
Gene name CG6523 gene product from transcript CG6523-RA
Gene symbol CG6523
Other names/aliases DmelCG6523
Grx3
Grx4
Species Drosophila melanogaster
 Database cross references - CG6523
ExoCarta ExoCarta_34745
Vesiclepedia VP_34745
Entrez Gene 34745
 CG6523 identified in sEVs derived from the following tissue/cell type
Drosophila S2 cells 23035643    
 Gene ontology annotations for CG6523
Molecular Function
    protein-glutathione oxidoreductase (glutathione) activity GO:0141049 NAS
 Experiment description of studies that identified CG6523 in sEVs
1
Experiment ID 202
MISEV standards
IEM
Biophysical techniques
TSG10|RAB35|FLOT2
Enriched markers
Negative markers
Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23035643    
Organism Drosophila melanogaster
Experiment description Drosophila S2 cells secrete Wingless on exosome-like vesicles but the Wingless gradient forms independently of exosomes.
Authors "Beckett K, Monier S, Palmer L, Alexandre C, Green H, Bonneil E, Raposo G, Thibault P, Borgne RL, Vincent JP."
Journal name Traffic
Publication year 2012
Sample Drosophila S2 cells
Sample name Normal-Drosophila S2 tub-Wg
Isolation/purification methods Filtration
Ultracentrifugation
Sucrose density gradient
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for CG6523
  Protein Interactor ExoCarta ID Identification method PubMed Species
1 CG17568  
Two-hybrid Drosophila melanogaster
2 CG33672  
Two-hybrid Drosophila melanogaster
3 bin  
Affinity Capture-MS Drosophila melanogaster
4 CG33095  
Two-hybrid Drosophila melanogaster
5 CG8301  
Two-hybrid Drosophila melanogaster
6 Elba2  
Two-hybrid Drosophila melanogaster
7 bsh  
Affinity Capture-MS Drosophila melanogaster
8 Trs33  
Two-hybrid Drosophila melanogaster
9 ago  
Two-hybrid Drosophila melanogaster
10 Lmpt  
Two-hybrid Drosophila melanogaster
11 CIAPIN1  
Affinity Capture-MS Drosophila melanogaster
Two-hybrid Drosophila melanogaster
12 CG9133  
Two-hybrid Drosophila melanogaster
13 CG14655  
Two-hybrid Drosophila melanogaster
View the network image/svg+xml
 Pathways in which CG6523 is involved
No pathways found





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