Gene description for COPE
Gene name coatomer protein complex, subunit epsilon
Gene symbol COPE
Other names/aliases -
Species Bos taurus
 Database cross references - COPE
ExoCarta ExoCarta_338085
Entrez Gene 338085
UniProt Q28104  
 COPE identified in exosomes derived from the following tissue/cell type
Milk 23459212    
 Gene ontology annotations for COPE
Molecular Function
    structural molecule activity GO:0005198 IEA
    protein binding GO:0005515 IPI
Biological Process
    retrograde vesicle-mediated transport, Golgi to ER GO:0006890 TAS
    intra-Golgi vesicle-mediated transport GO:0006891 IDA
    ER to Golgi vesicle-mediated transport GO:0006888 IBA
    protein transport GO:0015031 IEA
Subcellular Localization
    nucleoplasm GO:0005654 IEA
    COPI vesicle coat GO:0030126 IDA
 Experiment description of studies that identified COPE in exosomes
1
Experiment ID 213
ISEV standards
✘ EV Biophysical techniques
✘ EV Cytosolic markers
✘ EV Membrane markers
✘ EV Negative markers
✘ EV Particle analysis
Identified molecule protein
Identification method Mass spectrometry
PubMed ID 23459212    
Organism Bos taurus
Experiment description Bovine milk proteome: Quantitative changes in normal milk exosomes, milk fat globule membranes and whey proteomes resulting from Staphylococcus aureus mastitis.
Authors Reinhardt TA, Sacco RE, Nonnecke BJ, Lippolis JD.
Journal name J Proteomics
Publication year 2013
Sample Milk
Sample name Staphylococcus aureus-infected-Milk
Isolation/purification methods Differential centrifugation
Ultracentrifugation
Filtration
Sucrose density gradient
FACS
Flotation density -
Molecules identified in the study Protein
Methods used in the study Mass spectrometry
 Protein-protein interactions for COPE
  Protein Interactor ExoCarta ID Identification method PubMed Species
No interactions are found.
 Pathways in which COPE is involved
PathwayEvidenceSource
COPI Mediated Transport IEA Reactome





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